Our serums are a great combination with Retin-Aor retinol moisturizers. These products heavily exfoliate the skin, and preparethe ground work for these serums to take full effect. If using Retin-A youshould apply your serum first, then the Retin-A, then your moisturizer. Whenusing a moisturizer with retinol, apply the serum first, then your retinolmoisturizer afterwards.